Compound atlas
Anti-aging

Matrixyl

Also known as · Palmitoyl pentapeptide-4

Cosmetic peptide
Half-life
2h
approx. mean t½
Dose range
Topical
typical, not prescriptive
Category
Anti-aging
primary use-case
Single-dose decay
t½ = 2h · first-order model
~8h
to clear
1× t½
50%
remaining
2× t½
25%
remaining
~4× t½
6%
remaining
0%25%50%75%100%0m2h4h6h8h10h

How a single dose clears, assuming first-order elimination. The half-life is the biggest driver of how often you dose — start a cycle to see your own cumulative concentration curve.

Overview

A topical signal peptide used in skincare to stimulate collagen and reduce fine lines.

Mechanism of action

Signals fibroblasts to upregulate collagen, elastin, and glycosaminoglycan production.

Typical protocol

Applied topically in serums; not injected.

Storage

Cool, dark; per formulation.

Disclaimer

This page summarizes publicly available information. None of it constitutes medical advice, prescription, or recommendation to acquire, possess, or use any compound. Many peptides described are research chemicals not approved for human use in the EU. Consult a licensed physician.