Liraglutide
Also known as · Victoza · Saxenda
to clear
How a single dose clears, assuming first-order elimination. The half-life is the biggest driver of how often you dose — start a cycle to see your own cumulative concentration curve.
A daily GLP-1 receptor agonist for diabetes and weight management; predecessor to weekly agents.
GLP-1 receptor agonism enhancing insulin secretion, suppressing glucagon, and reducing appetite.
Daily subQ; titrate 0.6 → 1.2 → 1.8 → 2.4 → 3.0 mg.
Refrigerated; in use, room temp up to ~30 days.
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Semaglutide
A long-acting GLP-1 receptor agonist for type-2 diabetes and weight management. Slows gastric emptying and suppresses appetite.
Tirzepatide
A dual GIP/GLP-1 receptor agonist with superior weight loss and glycemic control versus semaglutide in head-to-head trials.
Retatrutide
An investigational triple agonist (GIP/GLP-1/glucagon) showing the largest weight-loss figures yet in trials. Not yet approved.